منابع مشابه
Lamotrigine-related rash: an audit
s 423 Lamotrigine-related rash: an audit I. Wang*, G. Mawer? &J. Sander’ *School of Pharmacy; University of Bradford, Bradford, UK; t David Lewis Centre for Epilepsy Cheshire, UK; $ institute of Neurology National Hospital for Neurology and Neurosurgery, London, UK Purpose: 1. To estimate the incidence of serious and non-serious rashes associated with lamotrigine (LTG) treatment. 2. To identify...
متن کاملPotentially serious Lamotrigine-related skin rash.
OBJECTIVE To report our experience with lamotrigine (LTG)-related skin rash in children with epilepsy. METHODS We identified a series of consecutive children with epilepsy treated with LTG prospectively over a 5-year period ending 1st October 2005 at King Abdul-Aziz University Hospital and King Faisal Specialist Hospital and Research Center, Jeddah, Kingdom of Saudi Arabia. RESULTS Of 207 c...
متن کاملRechallenge with lamotrigine after initial rash
Eight patients rechallenged with lamotrigine after initial exposure which resulted in a skin rash are reported. On reintroduction of the lamotrigine, six of the patients had no recurrence of the rash. Of the other two patients, one had the occurrence of a mild fluctuating and qualitatively different skin rash on rechallenge. The other patient had developed a dose-related rash on initial challen...
متن کاملAn audit of lamotrigine use as first-line monotherapy
Lamotrigine is licensed for first-line monotherapy use in the United Kingdom but many physicians have been reluctant to use it because of its perceived increased cost over conventional first-line antiepileptic medication. Clinical trials, however, have suggested that it has equivalent efficacy to conventional drugs in this role, with a significantly reduced side effect profile. It has been the ...
متن کاملRisk of a lamotrigine-related skin rash: Current meta-analysis and postmarketing cohort analysis
PURPOSE We systematically reviewed studies to provide current evidence on the incidence and risk of skin rash in patients with LTG therapy. METHODS PubMed and Scopus databases, up to 15 March 2014 were searched to identify relevant studies. Eligible studies included prospective studies, retrospective studies and postmarketing reports, which included data of skin rash in patients with LTG ther...
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ژورنال
عنوان ژورنال: Seizure
سال: 1998
ISSN: 1059-1311
DOI: 10.1016/s1059-1311(05)80021-4